2001;71(1):290–4.Kato H, Miyazaki T, Nakajima M, Takita J, Kimura H, Faried A, et al. This site needs JavaScript to work properly. Ratio of invaded to removed lymph nodes as a predictor of survival in squamous cell carcinoma of the oesophagus. Please enable it to take advantage of the complete set of features! Evaluation of lymph node metastases in squamous cell carcinoma of the esophagus with positron emission tomography. In patients with a primary tumor in the lower thoracic esophagus, four false-negative LNs were detected in the superior mediastinum. Our present study demonstrates that 28% of patients who underwent esophagectomy with LN dissection without neoadjuvant treatment had LNs falsely diagnosed as negative for metastasis, which is consistent with an earlier study [Due to the complex development of the lymphatic network around the esophagus, LN metastasis of thoracic esophageal cancer widely distributes from the neck to the abdomen [Modalities such as endoscopic ultrasound (EUS), CT, and FDG-positron emission tomography (FDG-PET) are frequently used for LN diagnosis, and previous studies report that their diagnostic performance is not satisfactory.

Oxford, England: Wiley-Blackwell; 2009.Shimada H, Okazumi S, Matsubara H, Nabeya Y, Shiratori T, Shimizu T, et al. World J Surg. There were 129 false-negative LNs, of which 85 were detectable by preoperative computed tomography (CT). Preoperative clinical diagnosis of lymph node (LN) metastasis and subsequent pathological diagnosis are often not in agreement. 2016;21(2):283–8.Motoyama S, Mori K, Kamei T, Miura M, Hinai Y, Sato Y, et al. You can also search for this author in Preoperative staging of esophageal cancer: comparison of endoscopic US and dynamic CT. Radiology. False-negative LNs associated with upper thoracic tumors were found in the superior mediastinal region. 1991;156(2):297–302.Buenaventura P, Luketich JD.

2018;154(2):360–73.Tachimori Y, Ozawa S, Numasaki H, Ishihara R, Matsubara H, Muro K. et al; Registration Committee for Esophageal Cancer of the Japan Esophageal Society. You can also search for this author in Informed consent for use of CT data for analysis was obtained from all patients included in the present study.During the study period, we used two types of CT scanners: Discovery CT750HD or Discovery CT750HDA (GE Healthcare Japan, Tokyo, Japan). Cancer. 1991;181(2):419–25.Takashima S, Takeuchi N, Shiozaki H, Kobayashi K, Morimoto S, Ikezoe J, et al. Comparison between positron emission tomography and computed tomography in the use of the assessment of esophageal carcinoma. This highlights the difficulty of diagnosing LN metastasis in this regionRepresentative CT findings and microscopic findings of false-negative LN. Staging accuracy of esophageal cancer by endoscopic ultrasound: a meta-analysis and systematic review. However, false-negative LNs in the most frequently occurring sites are characterized by smaller short-axis, suggesting that accurate diagnosis cannot be made unless the diagnostic criteria for the short-axis are reduced in addition to shape and attenuation.Although restrictive to the most frequent regions of false-negative LNs occur, reducing size criterion and consideration of their shape and attenuation may contribute to improved diagnosis.Regardless of advances in the comprehensive treatment of esophageal cancer, overall survival and preoperative 5-year survival remain poor [The presence of false-negative LNs hinders the actual cancer status and selection of an appropriate treatment. Eur Radiol. When the short-axis diameter, shape, and attenuation patterns of the LNs were used as criteria for metastasis diagnosis, they were insufficient for an accurate diagnosis. 2001;25(4):424–31.Shimizu Y, Tsukagoshi H, Fujita M, Hosokawa M, Kato M, Asaka M. Long-term outcome after endoscopic mucosal resection in patients with esophageal squamous cell carcinoma invading the muscularis mucosae or deeper. Clipboard, Search History, and several other advanced features are temporarily unavailable. Esophagus. Dis Esophagus.

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